Bispecific antibodies continue immuno-oncology drive
نویسندگان
چکیده
Recent deals involving bispecific antibodies illustrate the growing breadth of cancer immunotherapy applications for this platform.
منابع مشابه
OncOlOgy – The Bispecific ApprOAch
In the days before the internet became public, the word processor was an enhanced writing instrument. Then electronic messaging came along, and the same box became a tool for creating content as well as delivering it. Could a similar shift be taking place in the field of antibody therapeutics? The modern antibody therapeutic is a monospecific compound that recognises a single antigen on an inva...
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Monoclonal antibodies have emerged as a very successful class of therapeutic agents. In their native format, monoclonal antibodies are monospecific in that they recognize only one epitope, but their Fc domain also binds to FcfR-expressing cells. Attempts to improve the cytotoxicity of antibodies, particularly in the cancer field, have led to the design of bispecific antibodies: this can occur t...
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ژورنال
عنوان ژورنال: Biopharma Dealmakers
سال: 2021
ISSN: ['2730-6275', '2730-6283']
DOI: https://doi.org/10.1038/d43747-021-00096-w